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16: The Molecular Basis of Inheritance
This activity contains 8 questions.
In his work with pneumonia-causing bacteria and mice, Griffith found that
the protein coat from pathogenic cells was able to transform nonpathogenic cells.
the polysaccharide coat of bacteria caused pneumonia.
some substance from pathogenic cells was transferred to nonpathogenic cells, making them pathogenic.
bacteriophages injected DNA into bacteria.
heat-killed pathogenic cells caused pneumonia.
What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?
The origins of replication occur only at the 59 end.
DNA polymerase can join new nucleotides only to the 39 end of a growing strand.
DNA ligase works only in the 39 S59 direction.
Helicases and single-strand binding proteins work at the 59 end.
Polymerase can work on only one strand at a time.
In analyzing the number of different bases in a DNA sample, which result would be consistent with the base-pairing rules?
A = G
G = T
A + G = C + T
A = C
A + T = G + T
The elongation of the leading strand during DNA synthesis
does not require a template strand.
progresses away from the replication fork.
produces Okazaki fragments.
occurs in the 39 S59 direction.
depends on the action of DNA polymerase.
In a nucleosome, the DNA is wrapped around
a thymine dimer.
cells grown on
N medium are transferred to
N medium and allowed to grow for two more generations (two rounds of DNA replication). DNA extracted from these cells is centrifuged. What density distribution of DNA would you expect in this experiment?
one intermediate-density band
one low-density band
one high-density and one intermediate-density band
one low-density and one intermediate-density band
one high-density and one low-density band
A biochemist isolates, purifies, and combines in a test tube a variety of molecules needed for DNA replication. When she adds some DNA to the mixture, replication occurs, but each DNA molecule consists of a normal strand paired with numerous segments of DNA a few hundred nucleotides long. What has she probably left out of the mixture?
The spontaneous loss of amino groups from adenine in DNA results in hypoxanthine, an uncommon base, opposite thymine. What combination of proteins could repair such damage?
telomerase, primase, DNA polymerase
nuclease, telomerase, primase
nuclease, DNA polymerase, DNA ligase
telomerase, helicase, single-strand binding protein
DNA ligase, replication fork proteins, adenylyl cyclase
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