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Chapter 8: The Cellular Basis of Reproduction and Inheritance
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This activity contains 68 questions.
Most of an organism's DNA is carried by its _____.
endoplasmic reticulum
chromosomes
ribosomes
nucleoli
mitochondria
Who wrote that "every cell originates from another existing cell like it."?
Watson
Virchow
Beadle
Crick
Franklin
The term
binary fission
is best applied to _____.
nuclear chemistry
plants
prokaryotes
mitosis
chromosomes
In bacterial cells, binary fission involves _____.
prophase, metaphase, anaphase, and telophase
disintegration of the nuclear membrane
distribution of a copy of the single parental chromosome to each daughter cell
formation of a cell plate
formation of a spindle apparatus
A human bone marrow cell, in prophase of mitosis, contains 46 chromosomes. There are _____ chromatids.
46
92
23
23 or 46, depending on when during prophase you look
46 or 92, depending on when during prophase you look
Individual chromosome placement is usually observed with a light microscope during mitosis, even though cells spend more time in interphase. This is because _____.
the DNA has not been replicated yet
they have uncoiled to form long, thin strands
they leave the nucleus and are dispersed to other parts of the cell
sister chromatids do not pair up until division starts
the spindle must move them to the metaphase plate before they become visible
Chromatids are _____.
found only in aberrant chromosomes
held together by the centrioles
identical copies of each other if they are part of the same chromosome
not present in the Y sex chromosome, but are present in the X sex chromosome
composed of RNA
A cell biologist carefully measured the quantity of DNA in grasshopper cells growing in cell culture. Cells examined during the G
2
phase of the cell cycle contained 200 units of DNA. What would be the amount of DNA in one of the grasshopper daughter cells?
50 units
100 units
between 50 and 100 units
200 units
400 units
DNA replication occurs in _____.
prophase of both mitosis and meiosis
metaphase of meiosis only
the S phase of interphase
the G
1
phase of interphase in reproductive cells only
the cytokinesis portion of the cell's life cycle
Chromatids form _____.
during G
1
during G
2
during the S phase
at the start of mitosis
at the start of meiosis; chromatids are already formed before the M phase begins
In some organisms such as certain fungi and algae, cells undergo mitosis repeatedly without subsequently undergoing cytokinesis. What would be the consequence of this?
a decrease in chromosome number
an inability to duplicate DNA
division of the organism into many cells, most lacking nuclei
large cells containing many nuclei
a rapid rate of sexual reproduction
The function of mitosis is to produce daughter cells that _____.
are genetically identical to the parent cell (assuming no mutation has occurred)
have the same number of chromosomes as the parent cell but not the same genetic content
have a random assortment of maternal and paternal chromosomes
have the same number of chromatids as the parent cell had chromosomes
have half the number of chromosomes
Cytokinesis refers to _____.
division of all the parts of the cell
division of the nucleus
division of the cell outside the nuclear material
reduction in the number of chromosomes
cell movement
In the telophase of mitosis, the mitotic spindle breaks down and the chromatin uncoils. This is essentially the opposite of what happens in _____.
prophase
interphase
metaphase
S phase
anaphase
At which point do centrosomes begin to move apart to the opposite poles of the cell in a dividing human liver cell?
S phase
G
2
phase
prophase
metaphase
anaphase
The phase of mitosis during which the chromosomes move toward separate poles of the cell is _____.
telophase
anaphase
metaphase
prophase
cytokinesis
During cell division, what role do centrosomes play?
They organize the microtubules.
They cause cytokinesis via the concentric shortening of microtubules.
They are required for DNA replication.
They are the structures that hold the two sister chromatids together.
They are responsible for dissolving the nuclear membrane.
One event occurring during prophase is _____.
the beginning of the formation of the mitotic spindle
the synthesis of a new nuclear envelope
the alignment of chromosomes in a single plane
cytokinesis
division of the centromere
Single sister chromatids are found in cells at mitotic _____.
prophase and telophase
prophase and anaphase
prophase and metaphase
metaphase and anaphase
anaphase and telophase
Which of the following is a correct representation of an event that occurs in mitosis?
Prophase—chromosomes uncoil.
Metaphase—chromosomes line up on the equatorial plane.
Anaphase—the nuclear envelope disappears.
Prometaphase—there is movement of the chromosomes to the poles.
Telophase—chromosomes become more tightly coiled.
Which of the following occurs during mitosis?
Two genetically different daughter cells result.
Organelles replicate.
Chromatids separate.
Chromosomes replicate.
The cell divides into two separate cells.
At which stage of mitosis are chromosomes lined up in one plane in preparation for their separation to opposite poles of the cell?
prophase
metaphase
anaphase
telophase
interphase
The kinetochores _____.
are located at the center of the centrosome; their function is to organize tubulin into elongated bundles called spindle fibers
are the primary centromere structures that maintain the attachment of the sister chromatids prior to mitosis
are sites at which microtubules attach to chromosomes
are found as each spindle interlocks at the cell's equator and then move apart, causing the cell to elongate
attach to the ring of actin along the cytoplasmic surface of the plasma membrane, causing the actin to contract to form the cleavage furrow
Consider the photograph shown below. You can determine this is a plant cell rather than an animal cell because it has _____.
formed a cell plate
separated duplicated chromosomes during mitosis
microtubules
a well-organized spindle
formed a cleavage furrow
Cytochalasin B is a chemical that disrupts microfilament formation. This chemical would interfere with _____.
DNA replication
formation of the mitotic spindle
formation of a cleavage furrow
formation of the cell plate
binary fission
A cleavage furrow forms in an animal cell during _____.
anaphase
G
1
phase
cytokinesis
metaphase
prophase
Which of these factors inhibit(s) cell division?
growth factors
being attached to an extracellular surface
being attached to other cells of the same tissue
being completely surrounded by other cells
both growth factors and being attached to other cells of the same tissue
Consider the cell cycle shown below. Cells will usually divide if they receive the proper signal at a checkpoint in the _____ phase of the cell cycle.
M
G
1
S
G
2
cytokinesis
What is the difference between a benign tumor and a malignant tumor?
Benign tumors are a mass of essentially abnormal cells; malignant tumors are an abnormal mass of essentially normal cells.
Benign tumors do not metastasize; malignant tumors do.
Benign tumors metastasize; malignant tumors do not.
Benign tumors will not kill you; malignant tumors will.
Benign tumors spread beyond their original site; malignant tumors remain at their original site.
Observations of cancer cells in culture support the hypothesis that cancer cells _____.
do not exhibit density-dependent inhibition
produce molecules that inhibit the growth factors required for cell division
exhibit anchorage dependence
spend the majority of their time in a nondividing phase
divide in a controlled manner
How many pairs of autosomes do humans have?
23
22
2
1
It depends on the sex of the individual.
Which of the following is a normal human female?
XY
XXY
XXX
X
XX
In humans, the _____ determines the sex of the offspring because _____.
male … the male can contribute either an X or a Y chromosome
female … only the female provides cytoplasm to the zygote
male … the sperm can fertilize either a female egg or a male egg
female … only the female has two functional sex chromosomes
chromosome contribution from both parents … the offspring uses all the parents' chromosomes
An example of a cell that is 2
n
is a(n) _____.
haploid cell
somatic cell
gametophyte
sperm
ovum
After fertilization, the resulting zygote begins to divide by _____.
meiosis
mitosis
schizogony
binary fission
monogamy
When we say that an organism is haploid, we mean that _____.
its cells each have one chromosome
it has one half of a chromosome
its cells each have one set of chromosomes
its cells each have two sets of chromosomes
the chromosomes did not separate correctly doing meiosis
The diploid phase of the human life cycle begins with _____.
mitosis
meiosis
fertilization
a chromosomal mutation
the first division of the zygote
At a critical point in meiosis, the chromosomes do not replicate. This occurs between _____.
prophase I and metaphase I
metaphase I and anaphase I
anaphase I and telophase I
telophase I and prophase II
prophase II and metaphase II
In anaphase I, _____.
the sister chromatids move toward opposite poles
the sister chromatids move randomly toward either pole
homologous chromosomes move toward opposite poles
homologous chromosomes move toward the same pole
homologous chromosomes move randomly toward either pole
What is the typical result when a diploid cell undergoes meiosis?
two diploid cells
two haploid cells
four diploid cells
four haploid cells
two haploid cells and two diploid cells
In a cell containing 10 chromosomes, meiosis results in the formation of daughter cells containing _____ chromosomes.
5
10
20
40
0
At the end of telophase I of meiosis, as cytokinesis occurs, there are _____.
four haploid cells
two diploid cells
four diploid cells
one haploid ovum and three polar bodies
two haploid cells
Synapsis occurs during _____.
anaphase I
prophase I
telophase I
prophase II
metaphase I
During anaphase II, _____.
homologues separate and migrate toward opposite poles
sister chromatids separate and migrate toward opposite poles
nuclear membranes re-form
chromosomes line up in one plane
the cell is diploid
During anaphase I, _____.
homologues separate and migrate toward opposite poles
sister chromatids separate and migrate toward opposite poles
nuclear membranes re-form
chromosomes line up in one plane
the cell is haploid
Crossing over occurs during _____.
cytokinesis
metaphase I
prophase II
metaphase II
prophase I
An organism has a haploid chromosome number
n
= 4. How many tetrads will form during meiosis?
2
3
4
8
16
Which event occurs only during prophase I of the first meiotic division?
Chromosomes contain two chromatids attached to the same centromere.
Synapsis of homologous pairs occurs.
Nuclear membrane breaks down.
Replication of DNA takes place.
A spindle of microtubules forms.
The function of meiosis is to make _____.
exact copies of the parent cell
one cell with twice the number of chromosomes as the parent cell
four cells with the same chromosome number as the parent cell
four cells with a haploid number of chromosomes
two cells with a haploid number of chromosomes
Which of the following is a key difference between meiosis and mitosis?
Chromosomes align at the metaphase plate.
Chromosomes condense.
Chromosomes migrate to opposite poles.
A spindle apparatus forms.
Synapsis occurs.
Mitosis and cytokinesis result in the formation of _____; meiosis and cytokinesis result in the formation of _____.
four diploid cells … four haploid cells
two diploid cells … two haploid cells
two diploid cells … four haploid cells
two diploid cells … two diploid cells
four haploid cells … two diploid cells
Variation occurs when chromosomes are shuffled in _____.
mitosis
genetic drift
natural selection
mutation
meiosis
In humans, the haploid number of chromosomes is 23. Independent assortment has the possibility of producing _____ different gametes.
23
2
1 million
2
23
24
100,000
If the diploid number of chromosomes in a certain animal is 6 (2
n
= 6), there are three sets of two homologous chromosomes each, or three pairs. How do these three pairs align and separate in meiosis?
All members of each set move together.
All 12 chromatids move together.
Any two sister chromatids move together in meiosis II.
The first to move influences all the others.
They align and assort independently to form any of eight different combinations.
The major contribution of sex to evolution has been _____.
the reproduction of species
to provide a method that creates greater genetic variation
to provide a method permitting the inheritance of somatic mutations
to allow survival of the species
to prepare for the emergence of diploid terrestrial organisms
Consider the two mice shown below. They have the same chromosomes, carrying genes for the same traits in the same loci, but specifying different versions of the same traits—for example, coat and eye color. These chromosomes are called _____.
chromatic chromosomes
complementary chromosomes
differentiated chromosomes
homologous chromosomes
sister chromatids
In the picture below, the chromosomal region where the nonsister chromatids are crossing over is called a(n) _____.
inversion
homologue
kinetochore
chiasma
tetrad
Crossing over occurs during _____.
prophase I
metaphase I
anaphase I
prophase II
metaphase II
Crossing over is important because it _____.
holds tetrads together
ensures that homologous chromosomes pair up
allows the exchange of genes between homologous chromosomes
prevents variation in gametes
is necessary for the attachment of chromosomes to the spindle
Unless the chromosomes were stained to show band patterns, a karyotype would usually be
unable to show
_____.
an extra chromosome
a large part of a chromosome duplicated
a missing chromosome
an inversion
the attachment of a large part of a chromosome to another chromosome
Consider the photograph of a karyotype. This is _____.
an individual's physical traits
a means of determining a person's phenotype
all the possible gametes a person could produce
a photograph of all a person's chromosomes
a list of all the genes a person carries
Why are individuals with an extra chromosome 21, which causes Down syndrome, more numerous than individuals with an extra chromosome 3 or chromosome 16?
There are probably more genes on chromosome 21 than on the others.
Chromosome 21 is a sex chromosome, and chromosomes 3 and 16 are not.
Down syndrome is not more common, just more serious.
Extra copies of the other chromosomes are probably fatal.
Nondisjunction of chromosomes 3 and 16 probably occurs more frequently.
Each cell in an individual with Down syndrome contains _____ chromosomes.
3
22
24
45
47
During meiosis, homologous chromosomes sometimes "stick together" and do not separate properly. This phenomenon is known as _____.
cellular sterility
meiotic failure
gametic infertility
nondisjunction
sticky chiasmata
Down syndrome can be the result of _____.
nondisjunction of chromosome 21 during meiosis
occurrence of meiosis without cytokinesis
a deletion in chromosome 21
an extra cycle of DNA synthesis during the S phase
deletion of chromosome 21
Which of the following indicates Turner syndrome?
XYY
XO
YO
XY
XXY
If a fragment of a chromosome breaks off and then reattaches to the original chromosome at the same place but in the reverse direction, the resulting chromosomal abnormality is called _____.
a deletion
an inversion
a reciprocal translocation
a nondisjunction
polyploidy
The exchange of parts between nonhomologous chromosomes is called _____.
inversion
reciprocal translocation
signal transduction
transformation
duplication
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