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Medical Biotechnology
Learning Objectives
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After completing this chapter you should be able to:
- Provide examples of model organisms and explain why they are important.
- Describe how different karyotyping techniques can be used to test for chromosome abnormalities in fetuses or adults.
- Explain how molecular techniques can be used for genetic testing.
- Explain why single nucleotide polymorphisms may provide important clues about genetic diseases in humans.
- Define pharmacogenomics, and provide examples of why pharmacogenomics will change how many human genetic disease conditions will be treated in the future.
- Discuss how monoclonal antibodies may be used for treating disease.
- Understand the purpose of gene therapy, and compare and contrast in vivo and ex vivo gene therapy strategies and different gene delivery techniques.
- Recognize potential applications and limitations of gene therapy.
- Define regenerative medicine and provide examples of how cell and tissue transplantation and organ engineering can be used.
- Understand what stem cells are and describe how they can be isolated. Provide examples of possible therapies that may be developed from stem cells in the future.
- Compare and contrast therapeutic cloning and reproductive cloning.
- Briefly explain how molecular biology techniques and the Human Genome Project are being used to create human disease gene maps.
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