Lab 9: Renal System Physiology

1 .       Refer to Activity 1: Investigating the Effect of Flow Tube Radius on Glomerular Filtration. What happens to the glomerular filtration rate as the afferent radius is increased? 

2 .       If the efferent radius is increased, what happens to the glomerular filtration rate? 

3 .       Refer to Activity 2: Studying the Pressure on Glomerular Filtration. What happened to the glomerular filtration rate as the beaker pressure was increased? 

4 .       Why does an increase in pressure result in a faster glomerular filtration rate? Choose all that apply: 

5 .       Refer to Activity 3: Assessing Combined Effects on Glomerular Filtration. What happened when the valve was closed? 

6 .       What would happen to total glomerular filtration and urine production in a human kidney if all the collecting ducts were blocked? Choose all that apply: 

7 .       If a single nephron was blocked, how would this affect overall kidney function? 

8 .       If the glomerular filtration was zero, how would the kidneys be affected? 

9 .       What are ways the body could increase glomerular filtration rates in a human kidney? Choose all that apply.  

10 .       If the pressure were increased in the beaker, what could be done to keep the glomerular filtration rate constant? 

11 .       Refer to Activity 4: Exploring the Role of the Solute Gradient on Maximum Urine Concentration Achievable. In the presence of ADH, what happened to the urine concentration as the gradient concentration was increased? 

12 .       What factor limits the maximum possible concentration? 

13 .       Refer to Activity 5: Studying the Effect of Glucose Carrier Proteins on Glucose Reabsorption. What happened to the amount of glucose present in the urine as the number of glucose carriers was increased? 

14 .       What would happen if there was more glucose than could be transported by the available number of glucose carrier molecules? [Hint]

15 .       Why would we expect to find glucose present in the urine of a diabetic person? 

16 .       Refer to Activity 6: Testing the Effect of Hormones on Urine Formation. What happened to the urine volume when aldosterone was added? 

17 .       What happened to the urine volume when ADH was added? 

18 .       What happened to the amount of potassium present in urine when ADH was added? [Hint]

19 .       How would you compare the effects of aldosterone to the effects of ADH? 

20 .       Consider this situation: We want to reabsorb sodium ions, but do not want to increase the volume of the blood by reabsorbing water from the filtrate. Assuming that aldosterone and ADH are both present, how would you adjust the hormones to accomplish the task? 

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